聂玉哲

发布时间:2020-10-23文章来源: 浏览次数:

聂玉哲,讲师

联系方式:

E-mail:nieyuzhe@163.com

地址:黑龙江省哈尔滨市香坊区和兴路26号

99905i银河官方网(新逸夫教学楼)136房间

教育和训练经历:

1999/09-2003/0799905i银河官方网,生物科学专业(国家生物科学理科基地班),理学学士

2003/09-2006/0799905i银河官方网,园林植物与观赏园艺,农学硕士

2006/09-2010/0799905i银河官方网,发育生物学,理学博士

2009/01-2009/06赫尔辛基大学,联合培养博士

2015/07-2016/10南卡罗莱纳大学,博士后

工作经历:

2010/07至今,讲师

专业特长:

细胞生物学、蛋白质组学、分子生物学

●教学情况:

主讲本科《动物细胞工程与原理》、《细胞生物学实验课程》。参编教材《现代分子生物学实验模块指南》和《蛋白质分析实验技术指南》。

●科学研究方向:

胰腺癌细胞的增殖与抑制。

●近年研究课题:

microRNA124调控微量金属元素吸收抑制胰腺癌细胞的机制研究,黑龙江省重点基金,2017.10-2020.10。参加

●近年发表文章:

1. Lin Yang, Delin Kong, Mei He, Jiawei Gong, Yuzhe Nie, Sheng Tai, Chun-Bo Teng. MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma. Biochim Biophys Acta Mol Cell Res. 2020; doi:10.1016/j.bbamcr.2020.118826

2. Ze Yu, Hao Wang, Yilin Fang, Liangliang Lu, Minghao Li, Bingru Yan, Yuzhe Nie and Chunbo Teng. Molecular chaperone HspB2 inhibited pancreatic cancer cell proliferation via activating p53 downstream gene RPRM, BAI1, and TSAP6. Journal of Cellular Biochemistry. 2020, 121(3): 2318-2329.

3. Miao Liu, Wen Yu, Jing Jin, Mingjun Ma, Tiezhu An, Yuzhe Nie and Chun-Bo Teng. Copper promotes sheep pancreatic duct organoid growth by activation of an antioxidant protein 1-dependent MEK-ERK pathway. American Journal of Physiology-Cell Physiology. 2020, 318(4): C806-C816.

4.Yang L, Zhu Y, Kong D, Gong J, Yu W, Liang Y, Nie Y, Teng C-B: EGF suppresses the expression of miR-124a in pancreatic beta cell lines via ETS2 activation through the MEK and PI3K signaling pathways. International Journal Of Biological Sciences 2019, 15:2561-2575.

5.Yu Z, Wang H, Fang Y, Lu L, Li M, Yan B, Nie Y, Teng C: Molecular chaperone HspB2 inhibited pancreatic cancer cell proliferation via activating p53 downstream gene RPRM, BAI1, and TSAP6. Journal Of Cellular Biochemistry 2019.

6. Yu Z, Yu Z, Chen Z, Yang L, Ma M, Lu S, Wang C, Teng C, Nie Y: Zinc chelator TPEN induces pancreatic cancer cell death through causing oxidative stress and inhibiting cell autophagy. Journal Of Cellular Physiology 2019, 234:20648-20661.

7. Zhou RT, He M, Yu Z, Liang Y, Nie YZ, Tai S, Teng CB: Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways. Oncotarget 2017, 8:56351-56363.

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